Media & Graphics

Initiatives for addressing AMR in the environment: Reports from a joint WT, CDC, and UK-SIN project

Dear All: The United Kingdom Science and Innovation Network (UK-SIN), the United States Centers for Disease Control and Prevention (US-CDC), and the Wellcome Trust (WT) have recently released a white paper highlighting the potential for the environment (e.g., soil and water) to be a source of antimicrobial-resistant microbes that can affect human health: Executive Summary: Initiatives

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Public opinion poll (US): 70%+ agree need for government intervention addressing AMR, including support for AMR R&D

Dear All: IDSA and Research!America have worked together to conduct a broadly representative opinion poll in the United States regarding AMR. The project was supported by Pfizer and surveyed 1,004 adults in the US during October 2018. Key results: Less encouraging but probably an improvement from the past, 1/3rd of respondents thought antibiotics were effective

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33,100 deaths in EU/EEA during 2015 attributable to resistant bacteria

Dear All: Cassini et al. have just published a truly scary paper. Here’s the bulk of the abstract … I can’t improve on it. Methods: We estimated the incidence of infections with 16 antibiotic resistance–bacterium combinations from European Antimicrobial Resistance Surveillance Network (EARS-Net) 2015 data that was country-corrected for population coverage. We multiplied the number of bloodstream

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Superb Book To Read & Share: “Superbugs, An Arms Race Against Bacteria”

Dear All: I would like to draw your attention to a superb new book by William Hall, Anthony McDonnell, and Jim O’Neill. The names of the authors may be familiar as Jim O’Neill chaired the UK AMR Review and William Hall and Anthony McDonnell were two of the members of the core team who produced the Review’s seven excellent reports on

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CARB-X is seeking additional accelerators to expand support for its pipeline

Dear All: It is exciting to see that CARB-X today announced that it is seeking to partner with up to 6 additional accelerator organizations to expand its drug development and business support for its growing pipeline of early development antibacterial research projects. The Powered by CARB-X portfolio currently has 22 active projects in its pipeline, with more project announcements

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IDSA’s Faces of Antimicrobial Resistance (FAOR) report

Dear All: This one appears to have been released on 7 Mar but it just crossed my desk today. In brief, IDSA has assembled 13 patient stories into a well-written and illustrated .pdf. The centerpiece of the paper is this graphical history of AMR shown below.  Well done to IDSA for pulling these stories together

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Useful AMR graphics: Poirel 2017 and Marston 2016

Dear All: There’s a very comprehensive review of the polymyxins by Poirel, Jayol, and Nordmann just out in Clin Micro Reviews (http://cmr.asm.org/cgi/content/long/30/2/557). If you’re a fan of good quality graphics as way to tell the story of AMR, their Figure 4 is worth capturing! Ditto their Figure 5 of outbreaks of colistin-resistant, carbapenemase-producing K. pneumoniae.

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Preclinical pipeline overview / Help fund a movie about AMR!

Dear All: Two things today. First, Ursula Theuretzbacher, Miloje Savic, Christine Ardal, and Kevin Outterson have published in Nature Reviews Drug Discovery a brief but instructive snapshot of the global preclinical antibacterial pipeline. This report nicely complements the recent WHO analysis of the clinical pipeline that concluded that “the world is running out of antibiotics.” You’ll want to read the paper yourself (it’s

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