Lancet ID Commentary to the G20 on behalf of the DRIVE-AB Steering Committee

I am pleased to say that a commentary to the G20 on behalf of the DRIVE-AB Steering Committee has now gone live in the Online First section of Lancet Infectious Diseases. The article is not Open Access so you’ll have to download it for yourself (link below).

The commentary summarises some of DRIVE-AB’s preliminary findings that are pertinent to the G20 discussions as this list of recommendations:

  • Immediately fill the gap of US$250 million per year in push funding; existing mechanisms require additional financing and are well suited for an immediate in-flow of extra financing
  • Implement market entry reward pilots to learn about the operationalisation of such models
  • Request that regional and global banking institutions (such as the European Investment Bank and the World Bank) examine potential novel financial instruments to support further antibacterial R&D funding
  • Establish a mechanism for multinational coordination and collaboration
  • Develop health technology assessment processes and rules of reimbursement to consider the resistance situation and capture antibiotic societal value

DRIVE-AB’s complete findings will be published and presented at the DRIVE-AB conference in Brussels on Sept 5–6, 2017. 

Best wishes and stayed tuned for further developments! –jr

John H. Rex, MD | Chief Medical Officer, F2G Ltd. | Chief Strategy Officer, CARB-X | Expert-in-Residence, Wellcome Trust | Follow me on Twitter: @JohnRex_NewAbx

Upcoming events of note outside of the mainstream large meetings:

  • 10-11 July: FDA workshop on bacteriophage therapies
  • 19 July: FDA workshop on combination therapy for TB
  • 5-9 Sep: ASM-ESCMID conference on antibiotic R&D, including the CARB-X + GARDP Antibiotic Bootcamp
  • 13 Sep 2017 (DC): FDA-CDRH workshop on diagnostic devices for detecting antimicrobial susceptibility & resistance

Link to online article: http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(17)30404-8/abstract

Share

Lifeline, the Musical Story of Penicillin: A Review

Dear All, Last week I went to New York City to see one of the opening performances of Lifeline, The Musical, the world’s first musical telling the story of penicillin, Sir Alexander Fleming, and the rise of antibiotic resistance! This was my first time seeing the production in its entirety and it did not disappoint. The timing

WHO: AMR Policy Brief and Preclinical pipeline data call

Dear All, Supplementing and augmenting their review of the clinical and preclinical pipeline through 31 Dec 2023 (see the 15 June 2024 newsletter for details), WHO have now released: A call for data on preclinical antibacterial projects Scope: Traditional and non-traditional antibacterial candidates covering the WHO bacterial priority pathogens as well as other resistant pathogens of public health

UK Subscription model goes live! Value bands cover entire UK!

Dear All (with thanks to Kevin for leading on this newsletter and with a wonkish / long-read alert on this email … settle in for the ride!), Great news from TEAM UK! As of 12 August, the UK Subscription Program is no longer a pilot but is fully operational with an initial application deadline of

Needles and haystacks: Preclinical antibacterial pipeline review

Dear All, Just published in AAC is WHO’s updated review of the global preclinical pipeline. Here are the links you need to follow today’s discussion: The new WHO review: Gigante et al. “Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps”, https://doi.org/10.1128/aac.00535-24, AAC 2024. An excellent AAC podcast (overview webpage; YouTube video) discussing the WHO review. In

Scroll to Top