Dear All,WHO have just (2 Oct 2025) released a pair of reports on therapeutics and diagnostics for bacterial pathogens, with a focus on how these advance our tools for priority bacterial pathogens. Here are the links you need:WHO 2025 update on the preclinical and clinical antibacterial pipelineTitle: "Analysis of antibacterial agents in clinical and preclinical development: overview and analysis 2025"Data cut-off: 15 Feb 2025Links: Webpage about the report, the report itselfWHO 2025 update on available and pipeline antibacterial diagnosticsTitle: "Landscape analysis of commercially available and pipeline in vitro diagnostics for bacterial priority pathogens"Data cut-off: 15 Dec 2024Links: Webpage about the report, the report itselfReference:High-level webpage regarding both reportsThe AMR.Solutions summary of the various bacterial priority pathogen lists (PPLs)As always, there's a lot to digest ... but you can start with this topline summary:Clinical antibacterial pipelineThe pipeline is shrinking and fragile: WHO identified 90 agents (down from 97 in 2023) of which 50 are traditional antibiotics and 40 are non-traditional approaches.Gaps remain notable for oral therapies for outpatient use as well as in the area of pediatric formulationsInnovation remains limited: only 15 agents are considered innovative, but only 5 target WHO critical priority pathogens.Preclinical antibacterial pipeline232 programs are being advanced by 148 groups, over...