ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet


















How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
FDA: Early endpoints and late endpoints suggest a path to global regulatory convergence (Bart et al.)
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
Lancet: 10-20-30 targets to address AMR by 2030
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Melinta goes bankrupt / Never let a good crisis go to waste
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
UK to expand NHS Subscription Pilot! Consultation Period launches
The 6 meanings of “Lack of Access” (UNSLAP)
Draft EMA antibacterial guidance: Analysis
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet

The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet