UNGA 2024 and the AMR HLM:
Reports released in preparation

The HLM has now happened, but I am going to keep this webpage going (at least for now) as it is useful repository. Helpful post-HLM materials include the following:

  1. The 1 Oct 2024 newsletter for my review of the events at the HLM.
  2. CDC’s 4 Oct 2024 post-UNGA summary email. It provides informative highlights from several AMR-related side-meetings. 
  3. WHO’s 4 Oct 2024 AMR email summary. In addition to just being a good tour of WHO’s diverse array of activities, it starts with a quick overview of the HLM and then points to next steps (e.g., the November 2024 Ministerial meeting in Saudi Arabia).

During the run-up to the HLM (High-Level Meeting) on AMR during UNGA 2024 (the UN General Assembly, September 2024, see the 15 Apr 2023 newsletter for details), I thought it would be useful to have a list of major reports that had been released to inform those discussions. I am sure I am going to miss things (at least initially), so please drop me a note (john.rex@amr.solutions) if you want to see something added to this list. Thanks, —jr

  • Reports (mostly) Focused on AMR related to human health
  • Manufacturing
  • Stewardship and Access
    •  22 Mar 2021: Stewardship & Access Guide
      • From CARB-X, Wellcome, And Partners, this is the definitive guide
      • The 22 Mar 2021 newsletter is the best starting point; it also includes a video chat about the new guidelines
    • Feb 2024: Equitable & Responsible Access Roadmap
  • R&D: Push, Pull, People, and Evidence for Action
    • 07 Sep 2023: Overcoming Resistance
    • 21 Sep 2023: A New Grand Bargain to Improve the Antimicrobial Market for Human Health
      • Tackles the question of “Why would any given group take action to support an antibiotic ecosystem?” from the perspective of High-Income Countries (HICs), Low- and Middle-Income Countries (LMICs), Pharmaceutical companies, and International Organizations.
      • Webpage, report, and 5 Nov 2023 newsletter.
      • Report author: Center for Global Development (CGD)
    • 15 Nov 2023: Value and sustainability of antibiotics as essential tools for the healthcare system and people’s health
    • 08 Feb 2014: Leaving the Lab: Tracking the Decline in AMR R&D Professionals
    • 15 Feb 2024: 2024 AMR Preparedness Index Progress Report
    • 22 Feb 2024: The Economics of Antibiotic Resistance
    • 25 Mar 2024: Effective antibiotics for the Swiss health care system: today and in the future
    • 3 Apr 2024: Towards Specific Commitments and Action in the Response to Antimicrobial Resistance
    • 23 May 2024: The Lancet Series on Antimicrobial Resistance: The need for sustainable access to effective antibiotics
    • 12 Aug 2024: UK Subscription model goes live!
      • OK, it’s not a report per se but if it were it would be called “Here’s what can be done!”
      • The UK Subscription model really does set the pace for the rest of the world to follow
      • Webpage, 19 Aug 2024 newsletter
    • Aug 2024: Antibacterial pipeline trends and recommendations to enhance research and development
      • This policy brief does a good job of briefly (!) outlining 7 key points: the weak pipeline, the issues faced by developers, specific therapeutic gaps, the oral drug gap, the pediatric drug gap, the LMIC gap, and the non-traditional gap
      • Webpage, report, 1 Sep 2024 newsletter
      • Report author: WHO
    • 17 Sep 2024: Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050
      •  The team behind the Global Burden of Disease (GBD) project brings us the sobering news that AMR will kill 39m during 2025-2050 unless we act!
      • Link to article and to the 17 Sep 2024 newsletter
      • Report author: GBD 2021 Antimicrobial Resistance Collaborators
    • 27 Sep 2024: Forecasting the Fallout from AMR: Economic Impacts of Antimicrobial Resistance in Humans
      • This paper makes the economic case for action and can be summarized as “Without action, AMR costs go from $66b/yr to $159b/yr by 2050.” The deep economics are not often analyzed — this paper does a great job of articulating the “pay now or pay later” perspective.
      • Article itself and to the 27 Sep 2024 newsletter
      • Report author: Center for Global Development
  • Reports (mostly) focused on agriculture and food chain
  • January 2024: Tackling Antimicrobial Resistance in Food and Agriculture
    • A global survey of actions being taken by the Quadripartite, the Global Leaders Group, and the various National Action Plans on AMR in agricultural and food systems.
    • Webpage, report, and 27 Jan 2024 newsletter.
    • Report author: FAO

During the run-up to UNGA 2024 and the HLM on AMR (15 Apr 2023 newsletter for details), I thought it would be useful to have a list of major reports. I am sure I am going to miss things (at least initially), so please drop me a note (john.rex@13.43.35.2) if you want to see something added to this list.

 

 

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HLM on AMR at UNGA: The end of the beginning

Aside: Please refer to our UNGA 2024 webpage for additional post-HLM notes and updates. Dear All (and with thanks to Damiano for co-authoring), Last week in NYC, the UN General Assembly (UNGA) and all its surrounding activities created a lot of energy (not to mention a giant traffic jam)! After a series of side meetings

Without action, AMR costs go from $66b to $159b/yr by 2050

Dear All, A new paper from Anthony McDonnell and a team led by the Center for Global Development extends estimates of the health-related impact of AMR (e.g., death) to a consideration of the economic ($) cost of AMR. To follow the plot, here are the links you will need: The new paper: “Forecasting the Fallout

UN TV: You can watch the AMR High-Level Meeting at UNGA

Dear All, The AMR HLM (High-Level Meeting) at the UN General Assembly starts at 10a ET today.  You can watch it here on UN TV: https://webtv.un.org/en/asset/k11/k11knc6w2t Addendum: It’s available for replay at that same link. See also the 1 Oct 2024 newsletter for a review of the HLM. All best wishes, –jr John H. Rex, MD

PACE: A £5m funding round for diagnostics

Dear All, The peri-UNGA week is generating a lot of activity! Having about a year ago launched a £30m fund for support of AMR innovation with a call for therapeutic projects (30 Oct 2023 newsletter; I am told that awards will be announced soon), PACE (Pathways to Antimicrobial Clinical Efficacy, a joint project of LifeArc,

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