UNGA 2024 and the AMR HLM:
Reports released in preparation
The HLM has now happened, but I am going to keep this webpage going (at least for now) as it is useful repository. Helpful post-HLM materials include the following:
- The 1 Oct 2024 newsletter for my review of the events at the HLM.
- CDC’s 4 Oct 2024 post-UNGA summary email. It provides informative highlights from several AMR-related side-meetings.
- WHO’s 4 Oct 2024 AMR email summary. In addition to just being a good tour of WHO’s diverse array of activities, it starts with a quick overview of the HLM and then points to next steps (e.g., the November 2024 Ministerial meeting in Saudi Arabia).
During the run-up to the HLM (High-Level Meeting) on AMR during UNGA 2024 (the UN General Assembly, September 2024, see the 15 Apr 2023 newsletter for details), I thought it would be useful to have a list of major reports that had been released to inform those discussions. I am sure I am going to miss things (at least initially), so please drop me a note (john.rex@amr.solutions) if you want to see something added to this list. Thanks, —jr
- Reports (mostly) Focused on AMR related to human health
- Manufacturing
- 05 Jun 2023: Antibiotic Manufacturing Certification
- The AMR Industry Alliance has worked with BSI Standards to develop a certification process for safe discharge during antibiotic manufacturing.
- Press release, website, 25 Sep 2023 newsletter
- 05 Jun 2023: Antibiotic Manufacturing Certification
- Stewardship and Access
- 22 Mar 2021: Stewardship & Access Guide
- From CARB-X, Wellcome, And Partners, this is the definitive guide
- The 22 Mar 2021 newsletter is the best starting point; it also includes a video chat about the new guidelines
- Feb 2024: Equitable & Responsible Access Roadmap
- The AMR Industry Alliance‘s roadmap covers diagnostics, drugs, and procurement.
- The document itself
- 22 Mar 2021: Stewardship & Access Guide
- R&D: Push, Pull, People, and Evidence for Action
- 07 Sep 2023: Overcoming Resistance
- This one could have been subtitled “How Canada should Pull for new antibiotics”!
- Webpage, report, one-pager on the report, short slide deck, and 8 Sep 2023 newsletter.
- Report author: Canadian Council of Academies (CCA)
- 21 Sep 2023: A New Grand Bargain to Improve the Antimicrobial Market for Human Health
- Tackles the question of “Why would any given group take action to support an antibiotic ecosystem?” from the perspective of High-Income Countries (HICs), Low- and Middle-Income Countries (LMICs), Pharmaceutical companies, and International Organizations.
- Webpage, report, and 5 Nov 2023 newsletter.
- Report author: Center for Global Development (CGD)
- 15 Nov 2023: Value and sustainability of antibiotics as essential tools for the healthcare system and people’s health
- This one could have been subtitled “How Italy should Push and Pull as it takes the 2024 G7 chair“!
- Webpage, full report (in Italian), press release (in English), one-page policy brief (in English), and 7 Dec 2023 newsletter.
- Report author: The European House – Ambrosetti
- 08 Feb 2014: Leaving the Lab: Tracking the Decline in AMR R&D Professionals
- As you can infer from this title, this one summarizes the alarming multi-year decline in the number of active AMR R&D professionals.
- Press release, report, and 8 Feb 2024 newsletter.
- 15 Feb 2024: 2024 AMR Preparedness Index Progress Report
- Updates a 2021 survey on progress on National Action Plans, Push-Pull, Access, Appropriate Use, and Environmental Protection by 11 countries (Brazil, Canada, China, France, Germany, India, Italy, Japan, South Korea, UK, US).
- Press release, report, and 15 Feb 2024 newsletter.
- Report authors: Global Coalition on Aging (GCOA) and the Infectious Diseases Society of America (IDSA)
- 22 Feb 2024: The Economics of Antibiotic Resistance
- A superb tour of way an economist (and hence a Finance Minister) would view AMR as a Market Failure
- Webpage, paper, blog, and 28 Feb 2024 newsletter
- Report authors: For the Center for Global Development (CGD), Anthony McDonnell, Ranil Dissanayake, Katherine Klemperer, Flavio Toxvaerd, and Michael Sharland
- 25 Mar 2024: Effective antibiotics for the Swiss health care system: today and in the future
- This one could have been subtitled “How Switzerland should Push and Pull“!
- Webpage, primary report, and 5 April 2024 newsletter
- Report author: Swiss Roundtable on Antibiotics
- 3 Apr 2024: Towards Specific Commitments and Action in the Response to Antimicrobial Resistance
- Yes, it’s a long title! And, there is a subtitle: Recommendations for consideration by UN Member States in the outcome document of the High-level Meeting on AMR in September 2024
- Webpage, report, and 19 Apr 2024 newsletter
- There is also an important economic study that is used as supportive evidence. It is hard to find, but I do have this link: https://www.amrleaders.org/resources/m/item/annex-to-the-glg-report
- Report author: GLG AMR (Global Leaders Group on Antimicrobial Resistance)
- 23 May 2024: The Lancet Series on Antimicrobial Resistance: The need for sustainable access to effective antibiotics
- A superb collection of papers covering the ideas of (i) Sustainable (ii) Access to (iii) Effective Antibiotics. Look closely at those 3 words: such a good summary … it’s a deep read, but well worth your time!
- Webpage, 23 May 2024 newsletter, Fireside Chat with Ramanan Laxminarayan about the series and its messages
- 12 Aug 2024: UK Subscription model goes live!
- OK, it’s not a report per se but if it were it would be called “Here’s what can be done!”
- The UK Subscription model really does set the pace for the rest of the world to follow
- Webpage, 19 Aug 2024 newsletter
- Aug 2024: Antibacterial pipeline trends and recommendations to enhance research and development
- This policy brief does a good job of briefly (!) outlining 7 key points: the weak pipeline, the issues faced by developers, specific therapeutic gaps, the oral drug gap, the pediatric drug gap, the LMIC gap, and the non-traditional gap
- Webpage, report, 1 Sep 2024 newsletter
- Report author: WHO
- 17 Sep 2024: Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050
- The team behind the Global Burden of Disease (GBD) project brings us the sobering news that AMR will kill 39m during 2025-2050 unless we act!
- Link to article and to the 17 Sep 2024 newsletter
- Report author: GBD 2021 Antimicrobial Resistance Collaborators
- 27 Sep 2024: Forecasting the Fallout from AMR: Economic Impacts of Antimicrobial Resistance in Humans
- This paper makes the economic case for action and can be summarized as “Without action, AMR costs go from $66b/yr to $159b/yr by 2050.” The deep economics are not often analyzed — this paper does a great job of articulating the “pay now or pay later” perspective.
- Article itself and to the 27 Sep 2024 newsletter
- Report author: Center for Global Development
- 07 Sep 2023: Overcoming Resistance
- Reports (mostly) focused on agriculture and food chain
- January 2024: Tackling Antimicrobial Resistance in Food and Agriculture
- A global survey of actions being taken by the Quadripartite, the Global Leaders Group, and the various National Action Plans on AMR in agricultural and food systems.
- Webpage, report, and 27 Jan 2024 newsletter.
- Report author: FAO
- About the AMR HLM (High-Level Meeting)
- 23 Jan 2024: Resolution to support an HLM on AMR
- 2 Feb 2024: Letter from the President of the General Assembly announcing the HLM
During the run-up to UNGA 2024 and the HLM on AMR (15 Apr 2023 newsletter for details), I thought it would be useful to have a list of major reports. I am sure I am going to miss things (at least initially), so please drop me a note (john.rex@13.43.35.2) if you want to see something added to this list.
Share
HLM on AMR at UNGA: The end of the beginning
Aside: Please refer to our UNGA 2024 webpage for additional post-HLM notes and updates. Dear All (and with thanks to Damiano for co-authoring), Last week in NYC, the UN General Assembly (UNGA) and all its surrounding activities created a lot of energy (not to mention a giant traffic jam)! After a series of side meetings
Without action, AMR costs go from $66b to $159b/yr by 2050
Dear All, A new paper from Anthony McDonnell and a team led by the Center for Global Development extends estimates of the health-related impact of AMR (e.g., death) to a consideration of the economic ($) cost of AMR. To follow the plot, here are the links you will need: The new paper: “Forecasting the Fallout
UN TV: You can watch the AMR High-Level Meeting at UNGA
Dear All, The AMR HLM (High-Level Meeting) at the UN General Assembly starts at 10a ET today. You can watch it here on UN TV: https://webtv.un.org/en/asset/k11/k11knc6w2t Addendum: It’s available for replay at that same link. See also the 1 Oct 2024 newsletter for a review of the HLM. All best wishes, –jr John H. Rex, MD
PACE: A £5m funding round for diagnostics
Dear All, The peri-UNGA week is generating a lot of activity! Having about a year ago launched a £30m fund for support of AMR innovation with a call for therapeutic projects (30 Oct 2023 newsletter; I am told that awards will be announced soon), PACE (Pathways to Antimicrobial Clinical Efficacy, a joint project of LifeArc,