ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Lancet: 10-20-30 targets to address AMR by 2030
The 37,000-year view: Infections in Eurasia
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Developing systemic & inhaled antibiotics for lung infections
What does an antibiotic cost to develop? What is it worth? How to afford it?
Modeling the value of an effective antibiotic — Megiddo et al.
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet