ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Developing antibiotics for children: There are no easy answers
Modeling the value of an effective antibiotic — Megiddo et al.
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
Developing systemic & inhaled antibiotics for lung infections
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
NIAID workshop: What is a robust PK-PD package?
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet