ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Developing antibiotics for children: There are no easy answers
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
DTR Gram-negative infections: Are new antibiotics making a difference?
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
UK to expand NHS Subscription Pilot! Consultation Period launches
Economic modeling of the value of rapid diagnostics
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
FDA: Early endpoints and late endpoints suggest a path to global regulatory convergence (Bart et al.)
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
FDA analysis of 40-years of antibacterial development: Dheman et al.
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Lancet: 10-20-30 targets to address AMR by 2030
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet

The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet









