ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
FDA analysis of 40-years of antibacterial development: Dheman et al.
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
Economic modeling of the value of rapid diagnostics
The 37,000-year view: Infections in Eurasia
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
De-risking vaccine development: Insights spanning decades of experience
Draft FDA guidance on anti-infectives for children: It’s (mostly) all about PK and safety
Limits on measuring the impact of rapid antimicrobial susceptibility testing (AST)
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
Two new oral drugs for gonorrhea!
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet