ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
De-risking vaccine development: Insights spanning decades of experience
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
The 37,000-year view: Infections in Eurasia
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Modeling the value of an effective antibiotic — Megiddo et al.
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
Lancet: 10-20-30 targets to address AMR by 2030
Developing systemic & inhaled antibiotics for lung infections
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet