ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Limits on measuring the impact of rapid antimicrobial susceptibility testing (AST)
Lancet: 10-20-30 targets to address AMR by 2030
What does an antibiotic cost to develop? What is it worth? How to afford it?
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Push! Pull! Push! Pull! / Highlights from Davos 2018
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
Draft EMA antibacterial guidance: Analysis
In Praise of Non-Inferiority
Developing systemic & inhaled antibiotics for lung infections
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
Mirror Bacteria: An AMR threat of unprecedented magnitude
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet