ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
FDA analysis of 40-years of antibacterial development: Dheman et al.
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
The 6 meanings of “Lack of Access” (UNSLAP)
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
Mirror Bacteria: An AMR threat of unprecedented magnitude
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet