ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
Latest Newsletters
Latest Government Action





















R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
What does an antibiotic cost to develop? What is it worth? How to afford it?
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
The 37,000-year view: Infections in Eurasia
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Draft EMA antibacterial guidance: Analysis
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet