ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
FDA analysis of 40-years of antibacterial development: Dheman et al.
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
In Praise of Non-Inferiority
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
FDA workshop: Insights on inhaled antifungals and antibacterials
Lancet: 10-20-30 targets to address AMR by 2030
Limits on measuring the impact of rapid antimicrobial susceptibility testing (AST)
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet











