ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Modeling the value of an effective antibiotic — Megiddo et al.
The 6 meanings of “Lack of Access” (UNSLAP)
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
De-risking vaccine development: Insights spanning decades of experience
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
FDA analysis of 40-years of antibacterial development: Dheman et al.
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
In Praise of Non-Inferiority
DTR Gram-negative infections: Are new antibiotics making a difference?
The 37,000-year view: Infections in Eurasia
FDA workshop: Insights on inhaled antifungals and antibacterials
Draft EMA antibacterial guidance: Analysis
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet










