ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
Global survey of novel antibiotic reimbursement models / PASTEUR Act introduced to US House
De-risking vaccine development: Insights spanning decades of experience
The 37,000-year view: Infections in Eurasia
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
Economic modeling of the value of rapid diagnostics
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
FDA analysis of 40-years of antibacterial development: Dheman et al.
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
FDA workshop: Insights on inhaled antifungals and antibacterials
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet