ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Mirror Bacteria: An AMR threat of unprecedented magnitude
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
NIAID workshop: What is a robust PK-PD package?
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Developing antibiotics for children: There are no easy answers
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet