ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
Modeling the value of an effective antibiotic — Megiddo et al.
Mirror Bacteria: An AMR threat of unprecedented magnitude
Melinta goes bankrupt / Never let a good crisis go to waste
Draft FDA guidance on anti-infectives for children: It’s (mostly) all about PK and safety
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
NIAID workshop: What is a robust PK-PD package?
The 37,000-year view: Infections in Eurasia
Reimbursing for innovative antibiotics / Encouraging updates from the AMR conference
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet









