ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
In Praise of Non-Inferiority
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
FDA workshop: Insights on inhaled antifungals and antibacterials
NIAID workshop: What is a robust PK-PD package?
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
De-risking vaccine development: Insights spanning decades of experience
Mirror Bacteria: An AMR threat of unprecedented magnitude
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Draft EMA antibacterial guidance: Analysis
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet