ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
FDA: Early endpoints and late endpoints suggest a path to global regulatory convergence (Bart et al.)
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Push! Pull! Push! Pull! / Highlights from Davos 2018
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet












