ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
Modeling the value of an effective antibiotic — Megiddo et al.
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
Two new oral drugs for gonorrhea!
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
Economic modeling of the value of rapid diagnostics
Developing systemic & inhaled antibiotics for lung infections
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet