ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Lancet: 10-20-30 targets to address AMR by 2030
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
The 6 meanings of “Lack of Access” (UNSLAP)
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Reimbursing for innovative antibiotics / Encouraging updates from the AMR conference
Draft FDA guidance on anti-infectives for children: It’s (mostly) all about PK and safety
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
FDA analysis of 40-years of antibacterial development: Dheman et al.
Developing antibiotics for children: There are no easy answers
Two new oral drugs for gonorrhea!
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet












