ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
UK to expand NHS Subscription Pilot! Consultation Period launches
Global survey of novel antibiotic reimbursement models / PASTEUR Act introduced to US House
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Lancet: 10-20-30 targets to address AMR by 2030
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet