ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Economic modeling of the value of rapid diagnostics
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
UK to expand NHS Subscription Pilot! Consultation Period launches
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
Lancet: 10-20-30 targets to address AMR by 2030
What does an antibiotic cost to develop? What is it worth? How to afford it?
The 37,000-year view: Infections in Eurasia
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Mirror Bacteria: An AMR threat of unprecedented magnitude
NIAID workshop: What is a robust PK-PD package?
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet












