ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
UK to expand NHS Subscription Pilot! Consultation Period launches
In Praise of Non-Inferiority
Modeling the value of an effective antibiotic — Megiddo et al.
NIAID workshop: What is a robust PK-PD package?
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Draft FDA guidance on anti-infectives for children: It’s (mostly) all about PK and safety
Lancet: 10-20-30 targets to address AMR by 2030
FDA analysis of 40-years of antibacterial development: Dheman et al.
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet