ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Push! Pull! Push! Pull! / Highlights from Davos 2018
Melinta goes bankrupt / Never let a good crisis go to waste
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
NIAID workshop: What is a robust PK-PD package?
Developing antibiotics for children: There are no easy answers
What does an antibiotic cost to develop? What is it worth? How to afford it?
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
FDA analysis of 40-years of antibacterial development: Dheman et al.
Modeling the value of an effective antibiotic — Megiddo et al.
FDA workshop: Insights on inhaled antifungals and antibacterials
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet