ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
Draft EMA antibacterial guidance: Analysis
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
De-risking vaccine development: Insights spanning decades of experience
Modeling the value of an effective antibiotic — Megiddo et al.
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
NIAID workshop: What is a robust PK-PD package?
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
Developing antibiotics for children: There are no easy answers
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet