ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
UK to expand NHS Subscription Pilot! Consultation Period launches
De-risking vaccine development: Insights spanning decades of experience
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
Two new oral drugs for gonorrhea!
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet