ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
Developing antibiotics for children: There are no easy answers
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
Developing systemic & inhaled antibiotics for lung infections
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
FDA workshop: Insights on inhaled antifungals and antibacterials
De-risking vaccine development: Insights spanning decades of experience
In Praise of Non-Inferiority
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet