DTR Gram-negative infections: Are new antibiotics making a difference?
Dear All (and with thanks to Aaron Dane for co-authoring this newsletter AND inhale, exhale … this is going to be a long, wonkish, but VERY
24 April 2026 No Comments
Wonkish
Mirror Bacteria: An AMR threat of unprecedented magnitude
Dear All (wonkish but stick with it … I’m going to try very hard to de-wonk it; addendum: see also the follow-up newsletters, most recently
12 December 2024 No Comments
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
This newsletter is part of a series — here are the links to Part 1, (this one is Part 2), Part 3, Part 4, and Part 5. Also relevant
24 February 2020 No Comments
Limits on measuring the impact of rapid antimicrobial susceptibility testing (AST)
Dear All (and with thanks to Arjun Srinivasan for co-authoring this wonkish newsletter — prepare yourself! Know also that we’ve written a parallel newsletter entitled
27 May 2026 No Comments
Economic modeling of the value of rapid diagnostics
Dear All (and again with thanks to Arjun Srinivasan for co-authoring this pair of newsletters): In parallel with the newsletter discussing a recent paper on
27 May 2026 No Comments
In Praise of Non-Inferiority
Dear All (wonkish but intended for everybody to read and absorb): 27 Jan 2021 update: This topic now has its own YouTube video! As the
19 September 2020 No Comments
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
Dear All (and with thanks to Robert Bonomo and Patricia Bradford for guiding me on this newsletter; anything that’s correct is due to Patricia and
16 April 2026 No Comments
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
Note: See also these related newsletters: 20 Feb 2020 (link) on DTR as part of the language of resistance and 7 June 2020 (link) on
13 January 2019 No Comments
Two new oral drugs for gonorrhea!
Dear All (wonkish … but worth it … get ready to follow the links!), Greetings in the new year! As a marvelous way to end
13 January 2026 No Comments
The 37,000-year view: Infections in Eurasia
Dear All (prepare for something that is delightfully different and marvelously wonkish AND with thanks to Lance Price for co-authoring this newsletter), Continuing with the
17 September 2025 No Comments