Dear All (and with thanks to Patricia Bradford for taking the lead on this newsletter): Today, this paper in Nature takes us on a trip to the land of unintended consequences: Turner, A.M., Li, L., Monk, I.R. et al. Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin. Nature 635, 969–977 (2024). https://doi.org/10.1038/s41586-024-08095-4. A wonkish summary is found below