Dear All, At BEAM’s AMR Conference in Basel, Team CARB-X have today announced their 2025 funding round. Key points: Two themes: (i) Direct-acting small molecule therapeutics for Gram-negatives (same as in 2024) and (ii) diagnostics for typhoid fever in low-resource settings. 23 Mar 2025 newsletter update: The TPPs for both themes have been released: Small
Dear All (and with thanks to Damiano for co-authoring), We have exciting news from the G7 Health Ministers’ Meeting, which was held in person in Ancona on 9-11 October 2024, and the accompanying G7 Joint Finance and Health Ministers’ Meeting, which took place in a hybrid format on 10 October 2024. At the press conference closing
Dear All, CARB-X have opened their 2nd funding round for 2024! The Expression of Interest (EoI) deadline is 4 Oct 2024, so time is short! The 2nd round has the same 4 basic areas as the first round (see 6 Mar 2024 newsletter for reference): Therapeutics for Infections Caused by Gram-Negative Pathogens (WHO and CDC
Dear All, Heads up! Having just yesterday announced funding of its 100th project, CARB-X have today announced two funding rounds for 2024. With application dates of 18-29 Mar 2024 and 23 Sep-4 Oct 2024, applications are sought on 4 major areas (see extended details below my signature): Therapeutics for Infections Caused by Gram-Negative Pathogens (WHO and
Dear All (and with thanks to Damiano, Peter and Aleks for co-authoring), Some great news to start off 2024 on the right foot: the Novo Nordisk Foundation has announced that it will fund CARB-X with a three-year grant of USD 25 million! The Novo Nordisk Foundation joins four governments (Canada, Germany, the United Kingdom, and the United States)
Dear All, It’s been a busy 48 hours .. three (and a half) things for you! First up, you will find notes below my signature on today’s “Antimicrobial Resistance: Examining an Emerging Public Health Threat” hearing in the US House of Representatives. The recording of today’s hearing is now available on YouTube. It was a fabulous 2 hours
Dear All, Two quick items today. First, FDA have announced an Antimicrobial Drugs Advisory Committee on 17 April 2023 (9a-4.30p ET). The committee will “discuss new drug application (NDA) 216974, for sulbactam-durlobactam for injection, submitted by Entasis Therapeutics, Inc. The Applicant’s proposed indication is for the treatment of infections due to Acinetobacter baumannii-calcoaceticus complex including multidrug-resistant and
Please note that a very interesting Quality Improvement RFP has been added to the current funding opportunities listing with an application cut-off of 6 Oct … apologies for the late posting! Dear All, First up, CARB-X has at long last announced new funding rounds! As you’ll recall, CARB-X was recently funded for another 10 years by BARDA and Wellcome
Dear All, We have a 3-part discussion today on the theme of “I want a new drug … so how do I find it?” Off we go! First, the 14 June 2022 newsletter entitled “Leaky Pipe(lines) / When Is A Molecule A Drug” generated further discussions that are worth sharing: It was noted the microdosing
Dear All, Four big reports have recently been released and are very much worth reviewing. First, the Global AMR R&D Hub and the WHO AMR Team have written a report entitled “Incentivising the development of new antibacterial treatments“. This report is a response to a 2021 request by the G7 Finance Ministers for a report on