R&D Insight

Looking forward: The global pre-clinical antibacterial pipeline / How will we care for these precious jewels?

Dear All, Long note alert! There are two deep and deeply connected topics to share today. Refresh your coffee and settle in… Today’s first topic: Adding to the recent reviews of the clinical stage pipeline for both traditional products (link to the Sep 2019 Pew Charitable Trusts summary), and non-traditional products (link to an Aug 2019 newsletter summarizing

24 November 2019 No Comments

CDC’s 2019 update to its 2013 Antibiotic Resistance Report — A superb update!

Dear All, I’ve been hearing rumors about this report for a couple of weeks but now it’s out! The US CDC has released their 2019 update to their 2013 Antibiotic Resistance report. Go here for the full report. This report is clearly a labor of love on the part of Team CDC — the graphics, the patient

13 November 2019 No Comments

CMS foreshadows reimbursement actions/ GARDP’s 5-year plan / WHO toolkit / UK AMR Review update

Dear All, Today’s topics all share the theme of Less Talk, More Action! Here we go… First up … news from the US. I’ve written before about tweets from US CMS (Centers for Medicare and Medicare Services) administrator Seema Verma (link) on the need for changes in antibiotic reimbursement as well as the very concrete steps taken in

8 November 2019 No Comments

Ways to talk about AMR / Powerful new insights into messages that do (and do NOT) work

Dear All: Verbatim comments from interviews with 12,000 people in Germany, India, Japan, Kenya, the UK, the USA and Thailand: India: “[Antimicrobial resistance] is quite normal, no big thing, like malaria. It’s on a personal level, if you take antibiotics, your resistance will be on [the] lower side. If you are fit, your body resistance is more.” Germany: “Air pollution

30 October 2019 No Comments

BARDA seeks to support a VC-like mechanism for Medical Countermeasure (MCM) innovation / Your chance to provide input!

Dear All, BARDA is (yet again!) pushing the envelope with novel ways to support innovation. Their DRIVe group has just released an RFI in which they request input on their plans to create a VC-like mechanism through a third party to support innovation in the MCM (medical countermeasure) space. Go here for the complete RFI, but I’ll reproduce a

30 October 2019 No Comments

Save the date: 18-19 Nov 2019 FDA-IDSA-NIAID-Pew-sponsored workshop: “How can we improve antibacterial development?”

Dear All, Please mark your calendar now to be in the Washington, DC area on 18-19 Nov 2019 for a 2-day workshop at FDA’s White Oak Campus focused on enhancing the clinical trial enterprise for antibacterial drug development. Jointly co-sponsored by FDA, IDSA, NIAID, and Pew Trusts, this meeting will have a particular focus on (a)

4 October 2019 No Comments

ASM-ESCMID (3-6 Sep 2019, Boston): Post-meeting notes and annotated presentations

Dear All, Apologies for the delay, but I’ve held off on this note until the majority of the presentations from the 3-6 Sep 2019 ASM-ESCMID meeting (Boston) were online. You can now access the program, most of the presentations, and the meeting abstracts here. It was a wonderful meeting with over 400 attendees. And, please be sure

28 September 2019 No Comments

Superb podcast series: From “We can treat your cancer but you’ll die of infection” to “Tracking AMR by analyzing airplane toilet waste”

Dear All, I previously wrote (link) about the first of Jason Gale‘s 4-part podcast series on AMR. The whole series is now out and definitely worth your time. Each podcast is about 30 minutes long … please set aside a bit of time to listen to all four! Here they are: #1: In a detailed look at

27 September 2019 No Comments

DHHS Secretary Alex Azar, CDC, and Dame Sally Davies: An event to celebrate AMR fighters around the globe

Dear All, If you’re going to be in New York City on 23 Sep for the UN General Assembly, you are invited to join U.S. Health and Human Services Secretary, Alex Azar, experts from the U.S. Centers for Disease Control and Prevention, and hundreds of organizational and global leaders at an evening celebrating global AMR

16 September 2019 No Comments

Superb podcasts x 2: “Your cancer will be controlled, but you may die of infection” and “Pharma needs to be (and stay) engaged”

Dear All, Clear analyses by our colleagues in the science-focused media are invaluable ways to educate both ourselves and others: we learn new viewpoints while our non-technical friends and colleagues learn what keeps us up at night. On this note, we have two recently released 30-minute podcasts that are very much worth hearing and sharing.

15 September 2019 No Comments

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