John Rex

Canada says, “Let’s pull together!” in a major new report

Dear All (and with thanks to Kevin for co-authoring): Yesterday saw the release of a major new report on Pull incentives from Canada! The report’s cover art eloquently summarizes its key message: Well said … and proves that a picture really is worth 1,000 words! Here are the links you’ll need: The report’s webpage at the

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€100m HERA Invest fund; Sign to support PASTEUR; Superb AMR movie!

Dear All,  Expanding the available Push funding, the EU’s HERA (Health Emergency Preparedness and Response Authority) has created HERA Invest by allocating €100m in support early and late phases of clinical trials. HERA Invest is open on a rolling application basis to EU-based SMEs developing medical countermeasures that address one of the following cross-border health threats: (i)

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ENABLE-2: Rolling call for hit-to-lead projects is now open

Dear All, Summer is coming to a close … hard to believe it’s almost September! To get you going for the fall, the ENABLE-2 consortium has announced a call to support hit-to-lead compound development by researchers at publicly-funded European universities.  The call is focused on molecules with the potential to be direct-acting therapies for one or more of the following

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MHLW plan to pilot Pull incentives in Japan: Further details

Dear All, As a follow up the 19 Aug 2023 newsletter on MHLW’s work on Pull incentives (and with thanks to Yann Ferrise of GARDP for pointing out this out), we have an update in the 7 Aug 2023 edition of Nikkan Yakugyo (https://nk.jiho.jp/article/183026). It’s in Japanese and so again I must apologize for my lack

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Canada joins UK and Germany to support CARB-X; Japan’s MHLW investigates Pull!

Dear All, Some great news today! We have visible evidence of global government action in support of the addressing our antibiotic gaps. First, CARB-X has announced that Canada has now joined its coalition of funders with a pledge of $6.3m! Woot, woot! Go Team Canada!  Second, the UK and Germany have renewed their funding support with commitments of GBP

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Antibiograms: Polishing a cloudy crystal ball

Dear All, A recent paper by Hasegawa et al. and a multi-paper supplement, both in Clinical Infectious Diseases, combine to provide an interesting message. First, the paper by Hasegawa and colleagues. I’ve taken the title of this newsletter from an accompanying editorial by MacDougall who opens his commentary with “If there is one thing infectious

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EU Council Recommendation adopted! But what does it mean?

Dear All, During their recent turn to hold the EU presidency (1 Jan to 30 Jun 2023), the Swedes have steadily pushed AMR as one of their top priorities. As part of this, Sweden used their most recent presidency to release a motion to adopt a Council Recommendation on fighting AMR. Here are the parallel links that

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NCI’s natural product library: A 326,656 compound update!

Dear All, I wrote in 2018 about National Cancer Institute’s Natural Products Branch (NPB) and its program for Natural Product Discovery (NPNPD) as a resource for antimicrobial discovery. In brief, it’s a global collection of natural products that is available as a library of semi-pure natural product samples that comes pre-platted in 384-well plates. The deep idea behind

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