John Rex

EUR 20m funding for next-gen diagnostics for LRTIs (Novo Nordisk Foundation)

Dear All: I have just learned of a recently opened grant program from NNF (Novo Nordisk Foundation) that seeks to fund early-stage proof-of-concept on rapid, minimally invasive and affordable testing for LRTIs ((Lower Respiratory Tract Infections) at the point-of-care in global settings. The grant program actually opened just after ESCMID and I missed the announcement

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Economic modeling of the value of rapid diagnostics

Dear All (and again with thanks to Arjun Srinivasan for co-authoring this pair of newsletters): In parallel with the newsletter discussing a recent paper on the impact of rapid antimicrobial susceptibility testing (27 May 2026 newsletter, “Limits on measuring the impact of rapid AST”), we have release of an exceptionally well-done classic economic approach showing

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BARDA seeks info on Phase 2+ antifungals for Candida and Aspergillus

Dear All: As discussed in prior newsletters, BARDA is constantly working to ensure it has adequate medical countermeasures (MCMs) for a variety of possible threats. The titles of these newsletters give a quick review of their recent work — note in particular the Fireside Chat and the newsletter discussing the ongoing BAA (Broad Agency Announcement)

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CARB-X seeks two Assistant Directors of External Affairs

Dear All: Starting to get caught up after some time on vacation! For today, we have announcement by CARB-X of the posting of two openings for the role of Assistant Directors of External Affairs. Here are the links: Official webpage: https://jobs.silkroad.com/BU/External/jobs/316699 LinkedIn post: https://www.linkedin.com/posts/damianodefelice_job-opportunity-vacancy-share-7461081369562066944-tS7O A few excerpts from the job description: “The Assistant Director of

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AMR Science-Policy Symposia (ESCMID 2026): Smart policies for lean times

Dear All: ESCMID Global once again held an afternoon of sessions focused on the intersection of AMR-related science and policy. With an overall theme of “Smart policies for lean times,” the well-attended afternoon comprised a pair of workshops, a plenary session, and a networking reception (I’ll also note that there was a related integrated workshop [“Aligning

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Wellcome Leap: $50m for gut-sparing approaches to antibiotic delivery

Dear All: I’ve just learned of a funding call from Wellcome Leap entitled “Focused antibiotics.” The thesis of the call is that the resistance arises (at least in part) when the gut microbiome is exposed incidentally to an antibiotic intended for an infection elsewhere in body (e.g., the lungs). So, this project seeks to support

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Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations

Dear All (and with thanks to Robert Bonomo and Patricia Bradford for guiding me on this newsletter; anything that’s correct is due to Patricia and Robert; all the mistakes are mine!), This wonkish note has a short, simple version above my signature and then a longer version below by signature. The beta-lactam / beta-lactamase wizards will

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AMR Surveillance Data Challenge – Vivli 2026 Call for Projects!

Dear All, I’ve written before about the Vivli data challenge (2024 edition, 2025 edition) and am pleased to be able to say that there is a 2026 challenge! Here are the links you need: The data challenge overview’s home webpage The 20 Oct 2024 newsletter co-authored with Patricia Bradford that gives insights on how to

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