R&D Insight Archives • Page 16 of 39 • AMR.Solutions

BARDA Medical Countermeasures BAA: Substantial updates

Dear All (and yes, back-to-back newsletters … lots of action this week!): BARDA have today released a new version of their long-running BAA (Broad Agency Announcement, formerly BAA-18-100-SOL-00003) that seeks medical countermeasures (MCMs) for chemical, biological, radiological, and nuclear (CBRN) threats, pandemic influenza, and emerging infectious diseases. The new BAA is BAA-23-100-SOL-00004 and has been completely reorganized and

26 September 2023 No Comments

ENABLE-2: Rolling call for hit-to-lead projects is now open

Dear All, Summer is coming to a close … hard to believe it’s almost September! To get you going for the fall, the ENABLE-2 consortium has announced a call to support hit-to-lead compound development by researchers at publicly-funded European universities. The call is focused on molecules with the potential to be direct-acting therapies for one or more of the following

25 August 2023 No Comments

Antibiograms: Polishing a cloudy crystal ball

Dear All, A recent paper by Hasegawa et al. and a multi-paper supplement, both in Clinical Infectious Diseases, combine to provide an interesting message. First, the paper by Hasegawa and colleagues. I’ve taken the title of this newsletter from an accompanying editorial by MacDougall who opens his commentary with “If there is one thing infectious

18 August 2023 No Comments

AlphaFold: Highly accurate protein structure prediction for WHO priority pathogens

Dear All, I learned today from our colleagues at WHO that Alphafold has recently added the proteome of nearly all the WHO priority pathogens to their library of highly accurate prediction of protein structures. Alphafold was new to me and is amazing! Per our colleagues at WHO: AlphaFold is an AI system developed by DeepMind that

27 January 2022 No Comments

FDA posts 4 RFPs! MIC breakpoints, PRO for ABPA, dosing in obesity/CRRT!

Dear All, Whew … still catching up after all the activities of World Antimicrobial Awareness Week (WAAW)! More to follow on some of that great content, but for today we have the news that FDA has posted 4 RFPs! All have due dates of 21 Jan 2022: Optimizing dosing strategies for obese patients and in continuous

2 December 2021 No Comments

Comment on US 2023-2026 National Health Security Strategy

Dear All, The US Office of the Assistant Secretary for Preparedness & Response (ASPR) is looking for comments on the 2023-2026 National Health Security Strategy (NHSS). They would like input from stakeholders in public health, healthcare, emergency management, national security, non-governmental organizations, academia, and private industry. Their specific questions to consider are: What are the most critical national health

7 March 2022 No Comments

WHO RFP: Help build the One Health Research Agenda on AMR

Dear All, WHO are looking for multidisciplinary university groups or other scientific institutions to support the development of a One Health Priority Research Agenda on AMR! Per the RFP on the UN website (https://www.ungm.org/Public/Notice/146908), the terms of reference include scientific and methodological support for the following activities: Review of the grey literature and policy analysis of

2 October 2021 No Comments

21st Century Cures v2.0 — PASTEUR Act is embedded!

Dear All, Building on the success of the 21st Century Cures Act passed in 2016 and springboarding from a concept paper published in Science, U.S. Reps. Diana DeGette, D-Colorado, and Fred Upton, R-Michigan, have today introduced the 21st Century Cures Act v2.0! Here are the links you need: Discussion draft of the Cures 2.0 bill Cures 2.0

22 June 2021 No Comments

Ways to talk about AMR / Video chat with Maryn McKenna

Dear All, Explaining AMR to our colleagues is not easy! I wrote in a 30 Oct 2019 newsletter about what Wellcome Trust learned on this point when they interviewed 12,000 people in Germany, India, Japan, Kenya, the UK, the USA and Thailand — in brief, there are universal themes that improve the likelihood that your message will

11 June 2021 No Comments

Global Health Security: G7, BARDA Ventures, excellent ATMF report on saving small companies!

Dear All, On the theme of global health security, today’s note covers 3 exciting, overlapping items. Here we go… First, the G7 leaders have agreed to sign the Carbis Bay Declaration covering global health, economic stability, climate and more. Specifically related to health in a section entitled “End the pandemic and prepare for the future”, we have

14 June 2021 No Comments

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