R&D Insight

BARDA’s DRIVe is looking for you! Can you help them run a venture fund?

Dear All: I’ve written before about BARDA’s DRIVe initiative (Division of Research Innovation and Ventures, launched June 2018) that seeks to develop countermeasures for chemical, biological, radiological, and nuclear threats, as well as for pandemic influenza and emerging infectious diseases.  As a core part of this work, DRIVe Ventures seeks to link innovators and investors through creation of a VC-like

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JPIAMR: Network proposal call; BARDA: DRIVe Accelerator call

Dear All: I trust you are now home after ECCMID in Madrid … it was an excellent meeting. Two new funding opportunities have recently crossed my radar: brief summaries and one key link for each are here with some further details below my signature.  EU JPIAMR funding call: As part of its Virtual Research Institute

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Scary, Scarier, Scariest (Part 2): What can YOU do about it?

Long note alert— apologies! Get a cup of coffee and settle in… Dear All: My 22 Apr 2019 note entitled Scary, Scarier, Scariest: Achaogen / FT editorial / CBS “60 Minutes” on AMR (link) caused a number of you to write expressing your related concerns and frustrations. Many thanks for those thoughts! A core theme in those

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Clever pipeline visualization from Pew + New guidance documents from FDA

Dear All, Two very brief notes today… First, Pew Trusts continues to work to provide ways to understand the antibiotic pipeline. Building on their ongoing surveys (link), their latest contribution is a clever visualization tool that shows how antibiotics have moved forwards, backwards, and/or stopped during the period 2014-2018. Go here to see it in action and prepare to

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The UK jumps in with a subscription model for antibiotics!

Dear All: We had hints back in January that this was coming (see this post), but now it is really happening! In brief, UK’s NHS will test the world’s first subscription-style payment model in which payments delinked from volume are used to incentivise pharmaceutical companies to develop new drugs for resistant infections. Below my signature, I’ve

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NDM-1 in the Arctic / IACG seeks your views!

Dear All: Apologies for inundating with updates … the last few days have been very data rich! In case you missed it, McCann et al. (Env Internat, “Understanding drivers of antibiotic resistance genes in High Arctic soil ecosystems,” link) have found NDM-1, one of our more famous recent resistance genes, in the Arctic. As they state in their abstract, “The

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Start your engines! BARDA antibiotic procurement RFP / CARB-X 2019 funding round webinar

Dear All: Two things of note this afternoon… First, the previously noted BARDA RFP to acquire biothreat antibiotics is now posted here with submissions accepted through 21 June 2019: “Under this RFP, BARDA plans to support the procurement of antibiotic(s), which will either be delivered to the ASPR/SNS or maintained as VMI, using Project BioShield (PBS) funds. “PBS funds will also support

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