Dear All, At BEAM’s AMR Conference in Basel, Team CARB-X have today announced their 2025 funding round. Key points: Two themes: (i) Direct-acting small molecule therapeutics for Gram-negatives (same as in 2024) and (ii) diagnostics for typhoid fever in low-resource settings. 23 Mar 2025 newsletter update: The TPPs for both themes have been released: Small
24 Mar 2025 update: The call is live! It’s entitled “Development of a Rapid Point-of-care Antimicrobial Susceptibility Testing Diagnostic Medical Device (HADEA/2025/CPN/0006).” To apply, you must submit a request to participate by 12 May 2025; selected candidates who met the eligibility criteria will be able to submit a full technical tender. See the 24 Mar 2025 newsletter for a
Dear All, EMA have recently posted a call for tenders under which they seek to “procure the services of research organizations to perform studies on the quality, safety and efficacy of human and veterinary medicines that would provide complementary evidence to support regulatory decision-making.” It’s not specifically about AMR (or, indeed, about any particular therapy
Dear All, The Advisory Committee on Immunization Practices (ACIP) is scheduled to meet 26-28 Feb 2025 (see links below my signature for deeper background on ACIP and how it advises on vaccine use). At least as of today, the ACIP meeting is scheduled to occur as planned: it has a full agenda that covers meningococcal vaccine, influenza
Dear All, A huge announcement today backed by the combined power of the Gates Foundation, Novo Nordisk, and Wellcome! I am going to quote liberally from their materials: Responding to the problem of AMR, “… the Novo Nordisk Foundation (NNF), Wellcome, and the Gates Foundation (GF) are jointly launching a new initiative, Gram-Negative Antibiotic Discovery
Dear All, Sadly, I must report that the 27th meeting of PACCARB (the US Presidential Advisory Council on Combatting Antibiotic-Resistant Bacteria) planned for 28-29 Jan 2025 has been cancelled “as the new Administration considers its plan for managing federal policy and public communications.” This 22 Jan 2025 article in the New York Times provides additional details
Dear All, Three things for today along with some great acronyms! To start, we have an announcement of the first ever National One Health Framework to Address Zoonotic Diseases and Advance Public Health Preparedness in the United States (NOHF-Zoonoses) (website, .pdf of the framework). As a reminder, a zoonosis is an infection that jumps from
Dear All, I wrote in the 1 Dec 2024 newsletter about the excellent paper by Baraldi et al. that introduced us to the 6 possible meaning of “lack of access.” Since that newsletter, a bit of back-and-forth has produced a UNSLAP as a pronounceable acronym for the 6 meanings: (U)nregistered, (N)ever registered (or, not registered),
Dear All (wonkish but stick with it … I’m going to try very hard to de-wonk it; addendum: see also the follow-up newsletters, most recently on 22 Dec 2025), In an absolutely terrifying paper and technical report in today’s issue of Science, we are introduced in detail to the concept of “mirror” bacteria in which
Dear All, I’ve written before about the Vivli AMR Surveillance Data Challenge that seeks creative ways to reuse MICs from surveillance datasets (the 24 April 2023 newsletter covered the 2023 Challenge; the 15 June 2024 newsletter flagged the 2024 Challenge). As a reminder, Vivli is a clinical data sharing platform that was created in 2013 from a