R&D Insight

Pew’s SPARK goes live / FDA on Master Protocols and Adaptive Designs / CDC’s Fungal Awareness Week

Dear All: Potpourri! Four things of note… First, Pew’s SPARK (Shared Platform for Antibiotic Research and Knowledge) has now gone live. Seeking to address a core issue in Pew’s Scientific Roadmap for Antibiotic Discovery, SPARK is a cloud-based sharing tool for data on how molecules enter and stay inside of Gram-negative bacteria. To learn more, mark your calendar

Read More »

Lord O’Neill’s 10 steps to control AMR, two years on / G20 calls for action

Dear All: About two years ago, Lord Jim O’Neill led the UK AMR review to its 7th and final report and proposed these 10 steps as the fundamental basis for controlling AMR: A massive global public awareness campaign Improve hygiene and prevent the spread of infection Reduce unnecessary use of antimicrobials in agriculture and their dissemination into the environment Improve global surveillance of drug resistance and antimicrobial consumption in humans and animals

Read More »

WHO wants your input on its draft TPPs for needed antibacterial agents

Dear All, WHO has developed a set of draft TPPs (target product profiles) for needed new antibiotics. As part of the process, they are now opening a public consultation. Here is the essential text from their announcement: “The World Health organization (WHO) is developing target products profiles (TPPs) for needed antibacterial agents, providing the public

Read More »

Three $10k prizes for initiatives that improve access / create demand for diagnostics in LMICs

Dear All: Following the precept (often attributed to Osler, but I can’t find it in his Principles and Practice 1892) that the 3 core elements of treatment are “diagnosis, diagnosis, and diagnosis,” FIND (Foundation for Innovative New Diagnostics) is an international non-profit organization that enables the development and delivery of diagnostic tests for poverty-related diseases, including TB, malaria,

Read More »

Your vote counts! Support the UN proposal for an AMR-focused Sustainable Development Goal (SDG) Indicator

Dear All, Your vote counts! The UN’s Inter-Agency and Expert Group on Sustainable Development Goal Indicators (IAEG-SDGs) is conducting an open consultation on proposals it is considering including in the 2020 Comprehensive Review and is seeking the global community’s comments on these proposals (link to summary web page). The 17 SDGs were adopted in 2015 and are really driving

Read More »

PACCARB wants to hear from you! Deadline, 7 Jan 2019

Dear All: The US Presidential Advisory Council on Combating Antimicrobial Resistant Bacteria (PACCARB) has released a request for information (RFI) in which it seeks comments on priority actions for the future. Here is the link to the Federal Register notice: https://www.federalregister.gov/documents/2018/11/23/2018-25435/notice-of-request-for-information-a-notice-by-the-presidential-advisory-council-on-combating In brief, PACCARB has pursued these 5 goals from the first US National Action

Read More »

Initiatives for addressing AMR in the environment: Reports from a joint WT, CDC, and UK-SIN project

Dear All: The United Kingdom Science and Innovation Network (UK-SIN), the United States Centers for Disease Control and Prevention (US-CDC), and the Wellcome Trust (WT) have recently released a white paper highlighting the potential for the environment (e.g., soil and water) to be a source of antimicrobial-resistant microbes that can affect human health: Executive Summary: Initiatives

Read More »

BARDA seeks to support a VC-like mechanism for Medical Countermeasure (MCM) innovation / Your chance to provide input!

Dear All, BARDA is (yet again!) pushing the envelope with novel ways to support innovation. Their DRIVe group has just released an RFI in which they request input on their plans to create a VC-like mechanism through a third party to support innovation in the MCM (medical countermeasure) space. Go here for the complete RFI, but I’ll reproduce a

Read More »
Scroll to Top