Note: See also these related newsletters: 13 Jan 2019 (link) on DTR as part of the language of resistance and 7 June 2020 (link) on using DTR to estimate antibiotic value. There is also a 5-minute DTR explainer on YouTube that you might find useful. Dear All (wonk-ish note alert!), Three technical points for your consideration
Note: See also these related newsletters: 20 Feb 2020 (link) on DTR as part of the language of resistance and 7 June 2020 (link) on using DTR to estimate antibiotic value. There is also a 5-minute DTR explainer on YouTube that you might find useful. Dear All: When thinking about studies of resistant pathogens, issues
Dear All, During the 18-19 Nov 2019 FDA-IDSA-NIAID-Pew workshop on ways to enhance antibacterial research (link), we spent some time discussing the slow pace of updates to most guidelines. With the notable exception of the rapid guidance updates used in the HCV community (link), most guidelines are updated infrequently and each update feels like a Herculean
Dear All, As those of us who have had the privilege of standing at the bedside and delivering care know first hand, the magical power of a safe and effective antimicrobial agent is little short of magic. Sometimes, the (nearly) dead can get up and walk! With that idea in mind, I was just blown
Dear All: As you will hopefully recall from November 2019, Theuretzbacher et al. published a review of the preclinical pipeline that summarized data on 407 companies active in the preclinical R&D space during the window Sep 2016 through 1 May 2019. Go here for the newsletter about that paper and go here for my master summary
Dear All, Well, I think we can all agree that being grounded and shut away by COVID-19 is not exactly what any of us had in mind this spring! I certainly miss seeing everyone at the various events and I hope you are all keeping safe. But, staying home does offer a bit of time
Note that there is a follow-up newsletter that covers a post-webinar FAQ. After reading this newsletter as introduction, please go here for the follow-up newsletter. Dear All (and with thanks to Kevin Outterson for co-authoring this newsletter), Prior newsletters have covered the antibiotic evaluation procurement pilot being run by NICE and NHS England (go here for the
Dear All, Kevin Outterson and I recently shared our analysis of the NICE/NHS England pilot of an antibiotic procurement subscription model (link to that newsletter). The NICE/NHS team have now released a post-webinar FAQ document. Here is the link to the document … and I’ve also added the link to the initial webpage (cited just above) discussing
Dear All, 3 Apr 2020 update: Significant additional details on the pilot were shared via a 29 Mar 2020 webinar (link to newsletter) and then a FAQ document (link to newsletter). The game is definitely afoot! The hoofbeats of the cavalry bringing us the UK NHS antibiotic subscription model are definitely getting louder! As you
Dear All: I missed it personally, but by all reports the session on 3 June 2017 at ASM Microbe entitled “Development of New Drugs and Strategies for Hospital-Acquired Pneumonia Caused by MDR Pathogens” during ASM Microbe was an outstanding survey of this challenging area during which Shampa Das, Mike Dudley, and Sumati Nambiar gave great