ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
Reimbursing for innovative antibiotics / Encouraging updates from the AMR conference
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
FDA: Early endpoints and late endpoints suggest a path to global regulatory convergence (Bart et al.)
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
Draft EMA antibacterial guidance: Analysis
Developing antibiotics for children: There are no easy answers
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet