ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
FDA workshop: Insights on inhaled antifungals and antibacterials
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
In Praise of Non-Inferiority
Developing systemic & inhaled antibiotics for lung infections
Global survey of novel antibiotic reimbursement models / PASTEUR Act introduced to US House
Developing antibiotics for children: There are no easy answers
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
Lancet: 10-20-30 targets to address AMR by 2030
The 6 meanings of “Lack of Access” (UNSLAP)
Anti-Gram-negative beta-lactams in jeopardy: The rise of PBP3 mutations
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet