ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
NIAID workshop: What is a robust PK-PD package?
Reimbursing for innovative antibiotics / Encouraging updates from the AMR conference
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
Push! Pull! Push! Pull! / Highlights from Davos 2018
DTR Gram-negative infections: Are new antibiotics making a difference?
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
UK to expand NHS Subscription Pilot! Consultation Period launches
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet











