ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet


















Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Developing systemic & inhaled antibiotics for lung infections
Modeling the value of an effective antibiotic — Megiddo et al.
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
FDA analysis of 40-years of antibacterial development: Dheman et al.
Draft EMA antibacterial guidance: Analysis
Reimbursing for innovative antibiotics / Encouraging updates from the AMR conference
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Mirror Bacteria: An AMR threat of unprecedented magnitude
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet

The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet