ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
FDA: Early endpoints and late endpoints suggest a path to global regulatory convergence (Bart et al.)
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Reimbursing for innovative antibiotics / Encouraging updates from the AMR conference
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
UK to expand NHS Subscription Pilot! Consultation Period launches
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet